2018 Michigan Football Schedule
| Date | Opponent | Location |
| April 14 | Michigan spring game | Ann Arbor, Mich. |
| Sept. 1 | at No. 9 Notre Dame | Notre Dame, Ind. |
| Sept. 8 | Western Michigan | Ann Arbor, Mich. |
| Sept. 15 | SMU | Ann Arbor, Mich. |
| *Sept. 22 | Nebraska | Ann Arbor, Mich. |
| *Sept. 29 | at Northwestern | Evanston, Ill. |
| *Oct. 6 | Maryland | Ann Arbor, Mich. |
| *Oct. 13 | No. 6 Wisconsin | Ann Arbor, Mich. |
| *Oct. 20 | at No. 16 Michigan State | East Lansing, Mich. |
| Oct. 27 | Bye | Off |
| *Nov. 3 | No. 10 Penn State | Ann Arbor, Mich. |
| Nov. 10 | at Rutgers | Piscataway, N.J. |
| *Nov. 17 | Indiana | Ann Arbor, Mich. |
| *Nov. 24 | at No. 4 Ohio State | Columbus, Ohio |
| Dec. 1 | Big Ten championship | Indianapolis |
*Big Ten games