2025 Michigan State Football Schedule
Record: 3-5
| DATE | OPPONENT | TIME |
| Fri, Aug 29 | Vs Western Michigan | W 23-6 |
| Sat, Sep 6 | Vs Boston College | W 42-40 |
| Sat, Sep 13 | Vs Youngstown State | W 41-24 |
| Sat, Sep 20 | @ USC | L 45-31 |
| BYE | ||
| Sat, Oct 4 | @ Nebraska | L 38-27 |
| Sat, Oct 11 | Vs UCLA | L 38-13 |
| Sat, Oct 18 | @ Indiana | L 38-13 |
| Sat, Oct 25 | Vs Michigan | L 31-20 |
| Sat, Nov 1 | @ Minnesota | L 23-20 |
| Sat, Nov 15 | Vs Penn State | 3:30 p.m. |
| Sat, Nov 22 | @ Iowa | TBD |
| Sat, Nov 29 | Vs Maryland * | TBD |
All times EST. Schedule is subject to change.
Current AP Poll Top 25 rankings